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Also, the indole Main is substituted at R3 by using a carbonyl group which is also bonded into a napthalene moeity. Napthalene is usually a bicyclic structure of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it being a ketone. JWH-018 is undoubtedly an analog of THJ-018, wherein the Main indazole construction is substituted ha

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